The blade meets the fibres differently
With end grain, the wood fibres face upward. With edge grain, they run along the surface. That difference changes weight, feel, appearance and how much effort goes into the board.
Neither construction is automatically right for everyone. The best choice depends on how the board will be used.
End grain: more presence, more care
End grain is interesting for intensive cutting, good knives and a board that may stay visible. It is heavier, more complex to make and asks for regular care.
Edge grain: practical and direct
Edge grain can be lighter, calmer and easier to handle. For everyday kitchens where the board is moved often, it may be the better fit.
Decide by the moment, not the label
If you cut intensively and want a substantial work surface, end grain may make sense. If you want a reliable board for daily movement and cleaning, edge grain may be more practical.